3-hydroxy-3-methylglutaryl-coenzyme a has been researched along with (3S,5S,6E)-7-[3-(4-fluorophenyl)-1-(propan-2-yl)-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoic acid in 9 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (22.22) | 18.2507 |
| 2000's | 1 (11.11) | 29.6817 |
| 2010's | 5 (55.56) | 24.3611 |
| 2020's | 1 (11.11) | 2.80 |
| Authors | Studies |
|---|---|
| Asai, Y; Esaki, T; Hayashi, T; Iguchi, A; Jayachandran, M; Kano, H; Sumi, D; Thakur, NK | 1 |
| Côté, I; Gaudet, M; Grégoire, JP; Leach, A; Moisan, J; Vaillancourt, R | 1 |
| Frid, S; Lennernas, H; Lindahl, A; Ungell, AL | 1 |
| Musso, A; Poggi, A; Zocchi, MR | 1 |
| Cai, DQ; Kim, CS; Kim, DH; Kim, SK; Lee, KJ; Qi, XF; Qin, JW; Wu, Z; Yu, YH; Zheng, L | 1 |
| Dhople, VM; Kanugula, AK; Kotamraju, S; Ummanni, R; Völker, U | 1 |
| Abebayehu, D; Barnstein, BO; Chalfant, CE; Faber, T; Haque, TT; Kazmi, QA; Kolawole, EM; McLeod, JJ; Ndaw, V; Oskeritzian, CA; Paranjape, A; Qayum, AA; Ryan, JJ; Spence, AJ; Straus, DB; Sturgill, JL; Taruselli, M; Wijesinghe, DS | 1 |
| Bai, R; Bode, AM; Chang, X; Dong, Z; Li, X; Liu, K; Ma, W; Ryu, J; Song, Y; Wang, K; Wang, Q; Wang, T; Xia, Q; Zhang, T | 1 |
| Bilewicz, R; Matyszewska, D; Zaborowska, M | 1 |
9 other study(ies) available for 3-hydroxy-3-methylglutaryl-coenzyme a and (3S,5S,6E)-7-[3-(4-fluorophenyl)-1-(propan-2-yl)-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoic acid
| Article | Year |
|---|---|
A HMG-CoA reductase inhibitor improved regression of atherosclerosis in the rabbit aorta without affecting serum lipid levels: possible relevance of up-regulation of endothelial NO synthase mRNA.
Topics: Acyl Coenzyme A; Animals; Aorta; Arteriosclerosis; Body Weight; Cholesterol, Dietary; Endothelium, Vascular; Enzyme Inhibitors; Fatty Acids, Monounsaturated; Fluvastatin; Gene Expression Regulation, Enzymologic; Hypercholesterolemia; Indoles; Lipids; Male; Nitrates; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Nitrites; Rabbits; RNA, Messenger; Superoxide Dismutase; Up-Regulation | 1999 |
Preferred hydroxymethylglutaryl-coenzyme A reductase inhibitors: treatment-modification program and outcomes.
Topics: Acyl Coenzyme A; Anticholesteremic Agents; Canada; Cost-Benefit Analysis; Drug Administration Schedule; Fatty Acids, Monounsaturated; Fluvastatin; Humans; Hypercholesterolemia; Indoles; Medical Records; Military Personnel; Simvastatin; Treatment Outcome | 1999 |
No evidence for the involvement of the multidrug resistance-associated protein and/or the monocarboxylic acid transporter in the intestinal transport of fluvastatin in the rat.
Topics: Acyl Coenzyme A; Animals; Colon; Enzyme Inhibitors; Fatty Acids, Monounsaturated; Fluvastatin; Ileum; Indoles; Intestinal Absorption; Intestinal Mucosa; Male; Membrane Transport Proteins; Monocarboxylic Acid Transporters; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Niacin; Probenecid; Rats; Rats, Sprague-Dawley | 2000 |
Relevance of the mevalonate biosynthetic pathway in the regulation of bone marrow mesenchymal stromal cell-mediated effects on T-cell proliferation and B-cell survival.
Topics: Actins; Acyl Coenzyme A; Apoptosis; B-Lymphocytes; Blotting, Western; Bone Marrow Cells; Cell Communication; Cell Cycle; Cell Proliferation; Cells, Cultured; Coculture Techniques; Fatty Acids, Monounsaturated; Flow Cytometry; Fluvastatin; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Indoles; Lymphocyte Activation; Mesenchymal Stem Cells; Mevalonic Acid; Protein Prenylation; rhoA GTP-Binding Protein; Stromal Cells; T-Lymphocytes | 2011 |
HMG-CoA reductase inhibitors induce apoptosis of lymphoma cells by promoting ROS generation and regulating Akt, Erk and p38 signals via suppression of mevalonate pathway.
Topics: Acetylcysteine; Acyl Coenzyme A; Animals; Antioxidants; Apoptosis; Atorvastatin; bcl-2-Associated X Protein; Caspase 3; Cell Line, Tumor; DNA Fragmentation; Extracellular Signal-Regulated MAP Kinases; Fatty Acids, Monounsaturated; Fluvastatin; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Indoles; Lymphoma; Membrane Potential, Mitochondrial; Mevalonic Acid; Mice; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Poly(ADP-ribose) Polymerases; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Pyrroles; Reactive Oxygen Species; Signal Transduction; Simvastatin | 2013 |
Fluvastatin mediated breast cancer cell death: a proteomic approach to identify differentially regulated proteins in MDA-MB-231 cells.
Topics: Acyl Coenzyme A; Anticholesteremic Agents; Apoptosis; Breast Neoplasms; Caspase 3; Cell Line, Tumor; Chromatography, High Pressure Liquid; Electrophoresis, Gel, Two-Dimensional; Epithelial-Mesenchymal Transition; Fatty Acids, Monounsaturated; Female; Fluvastatin; Humans; Indoles; Metabolic Networks and Pathways; Mevalonic Acid; Mitogen-Activated Protein Kinase 1; Proteome; Tandem Mass Spectrometry; Vimentin | 2014 |
Fluvastatin Suppresses Mast Cell and Basophil IgE Responses: Genotype-Dependent Effects.
Topics: Acyl Coenzyme A; Animals; Apoptosis; Basophils; Cells, Cultured; Cytokines; Farnesyltranstransferase; Fatty Acids, Monounsaturated; Female; Fluvastatin; Genotype; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Immunoglobulin E; Indoles; Mast Cells; Mevalonic Acid; Mice; Mice, Inbred C57BL; Signal Transduction; Th2 Cells | 2016 |
Fluvastatin Inhibits HMG-CoA Reductase and Prevents Non-Small Cell Lung Carcinogenesis.
Topics: Acyl Coenzyme A; Adult; Aged; Animals; Apoptosis; Carcinogenesis; Carcinogens; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Female; Fluvastatin; Gene Knockdown Techniques; HEK293 Cells; Humans; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lung; Lung Neoplasms; Male; Mevalonic Acid; Mice; Middle Aged; Neoplasms, Experimental; Nitrosamines; RNA, Small Interfering; Xenograft Model Antitumor Assays | 2019 |
Model Lipid Raft Membranes for Embedding Integral Membrane Proteins: Reconstitution of HMG-CoA Reductase and Its Inhibition by Statins.
Topics: Fluvastatin; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Liposomes; Membrane Microdomains; Membrane Proteins; Water | 2022 |